Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length426 amino acids

Chemical FormulaC2123H3279N569O619S30

DescriptionStandard

        LLQPTPFELFFCDEMFNYCENMNVNSSNKQLNQYPMICFFRGDTFEYLYLNIVKYKTTKNLCMQIAKVDLPEPSVHFSPNVSGLDLSVSGLCVAVTGDWETHLGFIHDGGTFDMAVFDLSLRSVLTVNRDSGGRLSVFSVSCEADIESVDLRFYGGASLTYTNNNKQNTNNNKQNNNKGHCLPQICPPVEDAIQCLEQHLQAMEGITASSFNNTSTDSNRWCSSSKYVNQRVLQGSSEASRPATPFWPAFSIPVPRRMCFVGCVRVHANSASFAYYDSGHLQAFINDSMVPPFCPVRLNTSSMGRYIPQLPKLFPNLLMELQVYARQIPLFSFEPDFVKLNLPSGVKAFAVLPNATLTPLFKLKLAKNFLHALHARSHFRVQGVKESIHFLDSCLNGELLLSCMVTLPSCALVIMVNTTCRVENCT
    

Molecular Weight47639.13 Da

Isoelectric Point (pI)6.87

Net Charge (pH 7.0)-0.42

Net Charge (pH 7.4) -1.52

Charge Density (pH 7.0) -0.0010

GRAVY Index-0.05

Hydrophobic Moment 0.72

Boman Index0.08

Instability Index49.74

Aliphatic Index 82.79

Aromaticity 0.1033

Extinction Coeff. Reduced 34380.00

Extinction Coeff. Oxidized 35505.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0186317 VERIFIED: NO

Provenance & Taxonomy

OrganismNeogobius melanostomus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence