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MYP_165247
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Basic Information
Icosapeptide
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide Y family
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
20 amino acids
C100H147N29O30
Standard
Sequence
HKEDTLAFSEWGSPHAAVPR
Physicochemical Analysis
2235.41 Da
6.01
-1.06
-1.37
-0.0530
-0.80
0.33
-0.04
48.22
49.00
0.1000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
932.30
-9.12
32.0
31.0
67.0
159.0
7.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0030564 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone
RECORD: Rec_0067583 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0151711 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 70.0%, C 30.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0154621 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Pancreatic icosapeptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Receptor modulation Feeding regulator
Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Pancreatic icosapeptide (Homo sapiens): PMID 6366786 PMID6366786 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6366786/
RECORD: Rec_0316011 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
NPY
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
NPY-family Neuropeptide Neuromodulator
PMID6366786 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6366786/