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MYP_165187
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Basic Information
V13AD (V681 peptide derivative)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Wound healing/Regeneration ▸ Wound healing
Standard
26 amino acids
C136H223N35O34
Standard
Sequence
KWKSFLKTFKSAAKTVLHTALKAISS
Physicochemical Analysis
2892.44 Da
10.70
5.84
5.58
0.2247
0.00
0.65
0.04
6.56
86.54
0.1154
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1133.02
-9.50
42.0
41.0
99.0
205.0
5.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0361201 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0363467 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
D-Ala at 13
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus SAP0017
5 μg/mL
MIC
PMID15677462 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15677462/
RECORD: Rec_0371449 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis C621
2 μg/mL
MIC
PaperRational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. J Biol Chem. 2005 Apr 1;280(13):12316-29. doi: 10.1074/jbc.M413406200. PMID: 15677462. PMID15677462 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15677462/
RECORD: Rec_0383586 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
31.3 μg/mL
MHC
Paperhttps://pubmed.ncbi.nlm.nih.gov/18568863/ PMID18568863 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18568863/
RECORD: Rec_0391623 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
D-Ala at 13
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis C625
32 μg/mL
MIC
PMID15677462 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15677462/
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