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MYP_165130
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Basic Information
Charybdotoxin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
37 amino acids
C176H285N57O56S7
Standard
Sequence
EFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS
Physicochemical Analysis
4319.95 Da
9.13
4.86
4.55
0.1314
-0.83
0.54
-0.31
59.46
26.22
0.0811
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1894.43
-26.53
75.0
69.0
146.0
296.0
5.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0225857 VERIFIED: YES
Provenance & Taxonomy
Leiurus quinquestriatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID15118082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15118082/
RECORD: Rec_0282602 VERIFIED: YES
Provenance & Taxonomy
Leiurus quinquestriatus hebraeus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 27217
PMID15118082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15118082/
RECORD: Rec_0295916 VERIFIED: YES
Provenance & Taxonomy
Leiurus quinquestriatus [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0325599 VERIFIED: YES
Provenance & Taxonomy
Leiurus quinquestriatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus (Inhibition zone=3 mm incompletely inhibit in PH5.5, Inhibition zone=6 mm incompletely inhibit and Inhibition zone=1 mm completely inhibit in PH7.5 at 10 μg/well)
PMID15118082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15118082/
RECORD: Rec_0330854 VERIFIED: YES
Provenance & Taxonomy
Identified based on [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Bacillus subtilis, Staphylococcus aureus, Escherichia coli
PaperMultidimensional signatures in antimicrobial peptides.
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