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MYP_165130
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Basic Information
Charybdotoxin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
37 amino acids
C176H285N57O56S7
Standard
Sequence
EFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS
Physicochemical Analysis
4319.95 Da
9.13
4.86
4.55
0.1314
-0.83
0.54
-0.31
59.46
26.22
0.0811
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1894.43
-26.53
75.0
69.0
146.0
296.0
5.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0028265 VERIFIED: YES
Provenance & Taxonomy
Leiurus quinquestriatus hebraeus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli strain ML-35
PMID15118082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15118082/
RECORD: Rec_0043790 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0050108 VERIFIED: YES
Provenance & Taxonomy
Leiurus quinquestriatus hebraeus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 36082
PMID15118082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15118082/
RECORD: Rec_0051258 VERIFIED: YES
Provenance & Taxonomy
Leiurus quinquestriatus hebraeus [Animal]
Charybdotoxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperProc Natl Acad Sci U S A. 2004 May 11;101(19):7363-8. Epub 2004 Apr 26. | http://www.ncbi.nlm.nih.gov/pubmed/15118082 PMID15118082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15118082/
RECORD: Rec_0054322 VERIFIED: YES
Provenance & Taxonomy
Leiurus quinquestriatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli (Inhibition zone=2 mm incompletely inhibit in PH5.5, Inhibition zone=8 mm incompletely inhibit in PH7.5 at 10 μg/well)
PMID15118082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15118082/
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