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MYP_165089
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Basic Information
Ranatuerin-2AUa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
32 amino acids
C145H253N39O41S2
Standard
Sequence
GILSSFKGVAKGVAKNLAGKLLDELKCKITGC
Physicochemical Analysis
3262.93 Da
9.51
3.74
3.50
0.1168
0.36
0.58
0.14
-4.20
112.81
0.0312
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1299.92
-12.26
47.0
47.0
117.0
227.0
1.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0373785 VERIFIED: YES
Provenance & Taxonomy
Rana aurora aurora [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-32
Bio-Activity Profile
Antimicrobial
Streptococcus Group B
20 μM
MIC
PaperHost-defense peptides isolated from the skin secretions of the Northern red-legged frog Rana aurora aurora.
RECORD: Rec_0375789 VERIFIED: YES
Provenance & Taxonomy
Rana aurora aurora [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Streptococcus Group B HNTCC80130
20 μM
MIC
PMID15325526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15325526/
RECORD: Rec_0376346 VERIFIED: YES
Provenance & Taxonomy
Rana aurora [Animal]
Ranatuerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
27-32
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
20.0 μM
MIC
PaperJ.M. Conlon et al. / Developmental and Comparative Immunology 29 (2005) 83-90. Host-defense peptides isolated from the skin secretions of the Northern red-legged frog Rana aurora aurora
RECORD: Rec_0387218 VERIFIED: YES
Provenance & Taxonomy
Rana aurora [Animal]
Ranatuerin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
10 μM
MIC
PMID15325526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15325526/
RECORD: Rec_0393314 VERIFIED: YES
Provenance & Taxonomy
Rana aurora [Animal]
Ranatuerin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Candida albicans
40 μM
MIC
PMID15325526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15325526/
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