MYP_165076
Basic Information
VA3
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antifungal
Antiparasitic Antimalarial
Antiparasitic Antiprotozoal
Antiparasitic General antiparasitic Antiparasitic
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
not Standard
11 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWXWKXAKXAK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013884 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Candida parapsilosis ATCC 22019
31.25 μM
MIC
RECORD: Rec_0028956 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
VA3
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
Didehydrophenylalanine (ΔF)
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antimalarial
Plasmodium falciparum 3D7
15 μM
IC50; Fluorimetry (SYBR Green I)
RECORD: Rec_0032653 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Candida kefyr ATCC 2512
3.91 μM
MIC
RECORD: Rec_0053710 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Hemolytic
Human erythrocytes (15% Hemolysis at 50 microM, Human erythrocytes (20% Hemolysis at 100 microM
50 μM
Hemolysis
RECORD: Rec_0084162 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Aspergillus niger
67.31 μM
MIC
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