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MYP_164919
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Basic Information
Callinectin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
32 amino acids
C158H244N54O39S4
Standard
Sequence
WNSNRRFRVGRPPVVGRPGCVCFRAPCPCSNY
Physicochemical Analysis
3652.23 Da
10.66
5.72
5.46
0.1787
-0.51
0.57
-0.20
55.18
39.38
0.1250
6990.00
7240.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1498.62
-17.44
57.0
49.0
106.0
255.0
10.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007026 VERIFIED: YES
Provenance & Taxonomy
Callinectes sapidus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial
PMID21115038 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21115038/
RECORD: Rec_0068197 VERIFIED: NO
Provenance & Taxonomy
Hyas araneus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0073097 VERIFIED: YES
Provenance & Taxonomy
Callinectes sapidus [Animal]
Callinectin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperDev Comp Immunol. 2011 Apr;35(4):409-15 | http://www.ncbi.nlm.nih.gov/pubmed/21115038 PMID21115038 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21115038/
RECORD: Rec_0102502 VERIFIED: YES
Provenance & Taxonomy
Callinectes sapidus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PMID21115038;10373609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21115038/
RECORD: Rec_0232586 VERIFIED: YES
Provenance & Taxonomy
Callinectes sapidus [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
44-51). However, a complete sequence is only published in the new ref cited herein. Antibacterial activity was described in the 1999 paper (antibacterial in general?). The first Trp residue can be modified into three isoforms (hydroxy-N-formylkynurenine (major), N-formylkynurenine, and hydroxy-Trp (minor)). The pattern of the disulfide bonds has not been defined yet. The S-S bonds, as well as other possible chemical modifications, could be important for peptide stability
Bio-Activity Profile
Antimicrobial
PaperPrimary structure and cellular localization of callinectin; an antimicrobial peptide from the blue crab
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