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MYP_164917
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Basic Information
Leptoglycin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
22 amino acids
C79H136N22O23
Standard
Sequence
GLLGGLLGPLLGGGGGGGGGLL
Physicochemical Analysis
1762.06 Da
5.53
-0.24
-0.44
-0.0109
1.07
0.21
0.67
60.03
141.82
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
665.63
-7.34
22.0
23.0
58.0
124.0
1.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0266252 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]; Rana pentadactyla [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Citobacter freundii
75 μM
MIC
RECORD: Rec_0270464 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
50 μM
MIC
PMID19298834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19298834/
RECORD: Rec_0284767 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
50 μM
MIC
PaperLeptoglycin: a new Glycine/Leucine-rich antimicrobial peptide isolated from the skin secretion of the South American frog Leptodactylus pentadactylus (Leptodactylidae).
RECORD: Rec_0329652 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]; Rana pentadactyla [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
50 μM
MIC
RECORD: Rec_0336593 VERIFIED: NO
Provenance & Taxonomy
American frog [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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