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MYP_164917
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Basic Information
Leptoglycin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
22 amino acids
C79H136N22O23
Standard
Sequence
GLLGGLLGPLLGGGGGGGGGLL
Physicochemical Analysis
1762.06 Da
5.53
-0.24
-0.44
-0.0109
1.07
0.21
0.67
60.03
141.82
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
665.63
-7.34
22.0
23.0
58.0
124.0
1.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0153697 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Hemolytic
PMID19298834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19298834/
RECORD: Rec_0185820 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Citrobacter freundii
75 μM
MIC
PMID19298834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19298834/
RECORD: Rec_0198675 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa ATCC 9027
8 μM
MIC
PMID19298834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19298834/
RECORD: Rec_0199102 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Citrobacter freundii ATCC 8090
75 μM
MIC
PMID19298834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19298834/
RECORD: Rec_0239100 VERIFIED: NO
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antibiotic Antimicrobial Hemolytic Non-ribosomal
Qualitative functional evidence
PMID19298834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19298834/; https://www.uniprot.org/uniprotkb/P86267/entry; https://bblserver.org.in/ampdb/
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