Peptide Database

Peptide NameFMRFamide-related peptide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC52H79N17O14

DescriptionStandard

        GQERNFLRF
    

Molecular Weight1166.29 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0848

GRAVY Index-1.17

Hydrophobic Moment 0.57

Boman Index-0.39

Instability Index48.70

Aliphatic Index 43.33

Aromaticity 0.2222

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 543.40

LogP -5.03

H-bond Donors 19.0

H-bond Acceptors 15.0

Rotatable Bonds 39.0

Heavy Atoms 83.0

Ring Count 2.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0075358 VERIFIED: YES

Provenance & Taxonomy

OrganismLocusta migratoria [Animal]

FamilyFMRFamide related peptide

Tax ID7004

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0291511 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyFMRFamide-like peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0294979 VERIFIED: YES

Provenance & Taxonomy

OrganismLocusta migratoria [Animal]

FamilyFMRFamide-related peptide

Tax ID7004

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Myotropic

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0409196 VERIFIED: NO

Provenance & Taxonomy

OrganismLocusta migratoria [Animal]

Tax ID7004

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide