Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC443H733N109O126S2

DescriptionStandard

        MTKATDSRFYVLLSLSLLAVTSVALVIGNGSLIAANLGVSTGTAFTIVNFLDTWSSVATVITIVGMFTGVGTISAGVAASILAILKKKGKAKAAAF
    

Molecular Weight9666.34 Da

Isoelectric Point (pI)10.12

Net Charge (pH 7.0)4.50

Net Charge (pH 7.4) 4.27

Charge Density (pH 7.0) 0.0468

GRAVY Index1.06

Hydrophobic Moment 0.48

Boman Index0.40

Instability Index5.26

Aliphatic Index 126.04

Aromaticity 0.0729

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3710.56

LogP -36.36

H-bond Donors 134.0

H-bond Acceptors 133.0

Rotatable Bonds 319.0

Heavy Atoms 680.0

Ring Count 8.0

Amide Bonds 98.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0406661 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus altitudinis [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal