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MYP_164873
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
11 amino acids
C69H119N17O12
Standard
Sequence
KKVVFKVKFKK
Physicochemical Analysis
1378.79 Da
10.70
5.75
5.54
0.5231
-0.47
0.07
-0.31
-36.29
79.09
0.1818
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
510.44
-0.53
18.0
18.0
52.0
98.0
2.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0084200 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans 96-817
32 μg/mL
MFC
PMID11587795;10390226;25169965;10632060 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11587795/
RECORD: Rec_0085899 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Antibacterial
Mouse erythrocytes
500 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/10632060/ PMID10632060 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10632060/
RECORD: Rec_0088705 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
APD analysis reveals that this sequence is similar (80%) to PL-18 K: 55%, V: 27%, F: 18%. Chemical modification: N-terminal acetylation (XXE) and C-terminal amidation (XXA)
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis ATCC 12228
4 μM
MIC
PaperFunctional synergy of alpha-helical antimicrobial peptides and traditional antibiotics against Gram-negative and Gram-positive bacteria in vitro and in vivo.
RECORD: Rec_0090329 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
8 μM
MIC
PMID11587795;10390226;25169965;10632060 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11587795/
RECORD: Rec_0090965 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans 96-802
16 μg/mL
MFC
PMID11587795;10390226;25169965;10632060 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11587795/
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