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MYP_164863
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Basic Information
P1-Hp-1971
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C89H154N26O24
Standard
Sequence
TKPTLLGLPLGAGPAAGPGKR
Physicochemical Analysis
1972.33 Da
11.17
2.40
2.20
0.1141
-0.07
0.34
0.16
31.71
88.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
764.56
-8.20
25.0
27.0
59.0
139.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0060049 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas pulchellus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
8 μM
MIC
PaperAntimicrobial Peptides from Skin Secretions of Hypsiboas pulchellus (Anura: Hylidae).
RECORD: Rec_0063852 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 19.0%, E 9.5%, T 47.6%, C 23.8% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0213790 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas pulchellus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25929
8 μM
MIC
PMID24717080 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24717080/
RECORD: Rec_0222206 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas pulchellus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
16 μM
MIC
PMID24717080 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24717080/
RECORD: Rec_0284088 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas pulchellus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
13 μM
MIC
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