Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length250 amino acids

Chemical FormulaC1272H1957N287O376S13

DescriptionStandard

        KIISVLFVIFCVLSNTLTVVMQIDDLAEVDYSLSSLPAVFQPFIDLDLKGVVFPAGNYTDSPYMAASFRIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTVEMQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNIFDQKLMGSLCLNRLQFSLAHSNVGFFEVLLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight27702.69 Da

Isoelectric Point (pI)4.13

Net Charge (pH 7.0)-15.15

Net Charge (pH 7.4) -15.51

Charge Density (pH 7.0) -0.0606

GRAVY Index0.47

Hydrophobic Moment 0.55

Boman Index0.28

Instability Index43.27

Aliphatic Index 104.52

Aromaticity 0.1240

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0335107 VERIFIED: NO

Provenance & Taxonomy

OrganismCnemophilus loriae [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria