Peptide Database

Peptide Nameaurein 3.1.2

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC75H124N20O20

DescriptionStandard

        FDIVKKIAGHIAGSIG
    

Molecular Weight1625.91 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0529

GRAVY Index0.76

Hydrophobic Moment 0.60

Boman Index0.37

Instability Index32.14

Aliphatic Index 128.12

Aromaticity 0.0625

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 638.07

LogP -4.62

H-bond Donors 22.0

H-bond Acceptors 22.0

Rotatable Bonds 55.0

Heavy Atoms 115.0

Ring Count 2.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224264 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria aurea; Litoria raniformis [Animal]

FamilyAurein

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anticancer

PaperRozek T., Wegener K.L., Bowie J.H., Olver I.N., Carver J.A., Wallace J.C., Tyler M.J.;. "The antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2."; Eur. J. Biochem. 267:5330-5341. PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/