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MYP_164788
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Basic Information
NPG2000
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XRGGRLCYCRRRFCVCVGR
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009451 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
mPEG2000 [polyethylene glycol monomethyl ether(mPEG) 2000 Da] at 1; mPEG2000 [polyethylene glycol monomethyl ether(mPEG) 2000 Da]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. typhimurium 14028
64 μg/mL
MIC
PMID34196552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34196552/
RECORD: Rec_0052477 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
mPEG750 [polyethylene glycol monomethyl ether(mPEG) 750 Da] at 1; mPEG750 [polyethylene glycol monomethyl ether(mPEG) 750 Da]
Bio-Activity Profile
Hemolytic
human RBCs
>512 μg/mL
HC10
PMID34196552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34196552/
RECORD: Rec_0066273 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
mPEG2000 [polyethylene glycol monomethyl ether(mPEG) 2000 Da] at 1; mPEG2000 [polyethylene glycol monomethyl ether(mPEG) 2000 Da]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis 29212
128 μg/mL
MIC
PMID34196552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34196552/
RECORD: Rec_0077337 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
mPEG750 [polyethylene glycol monomethyl ether(mPEG) 750 Da] at 1; mPEG750 [polyethylene glycol monomethyl ether(mPEG) 750 Da]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli 987P
32 μg/mL
MIC
PMID34196552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34196552/
RECORD: Rec_0080000 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
mPEG2000 [polyethylene glycol monomethyl ether(mPEG) 2000 Da] at 1; mPEG2000 [polyethylene glycol monomethyl ether(mPEG) 2000 Da]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 25923
128 μg/mL
MIC
PMID34196552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34196552/
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