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MYP_164766
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Basic Information
Brevinin-1P
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
24 amino acids
C118H206N28O27S2
Standard
Sequence
FLPALIGIAAKALPSLLCKITKKC
Physicochemical Analysis
2513.20 Da
9.70
3.74
3.50
0.1557
1.12
0.55
0.34
34.61
146.67
0.0417
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
859.58
-3.37
31.0
33.0
83.0
175.0
3.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005665 VERIFIED: YES
Provenance & Taxonomy
Pelophylax fukienensis [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
18-24
Bio-Activity Profile
Antimicrobial Antibacterial
PaperT. Chen et al. / Genomics 87 (2006) 638-644. Cloning from tissue surrogates: Antimicrobial peptide (esculentin) cDNAs from the defensive skin secretions of Chinese ranid frogs Evidence URLhttps://www.uniprot.org/uniprotkb/Q2UXW0/entry
RECORD: Rec_0091150 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 58.3%, E 0.0%, T 16.7%, C 25.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0193245 VERIFIED: YES
Provenance & Taxonomy
Rana fukienensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 16139929 PMID16139929 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16139929/
RECORD: Rec_0205095 VERIFIED: NO
Provenance & Taxonomy
Rana plancyi fukiensis,Pelophylax plancyi fukiensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0224926 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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