Peptide Database

Peptide Name[L9]-P18 (analog of P18)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC119H190N28O19

DescriptionStandard

        KWKLFKKILKFLHLAKKF
    

Molecular Weight2316.96 Da

Isoelectric Point (pI)10.78

Net Charge (pH 7.0)6.84

Net Charge (pH 7.4) 6.58

Charge Density (pH 7.0) 0.3800

GRAVY Index-0.08

Hydrophobic Moment 0.83

Boman Index-0.02

Instability Index-2.36

Aliphatic Index 113.89

Aromaticity 0.2222

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 784.63

LogP 2.21

H-bond Donors 28.0

H-bond Acceptors 27.0

Rotatable Bonds 83.0

Heavy Atoms 166.0

Ring Count 6.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403071 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer

TargetEscherichia coli KCTC 1682

Activity12.5 μM

MethodMIC

RECORD: Rec_0408678 VERIFIED: YES