Peptide Database

Peptide NameBeta-defensin 132

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC467H744N138O131S8

DescriptionStandard

        MNFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTYCHWGETALFMCNASRKCCVSYSFLPKADLPRLIGNHWQSRRRNTQRKDKKQQTTVTS
    

Molecular Weight10644.27 Da

Isoelectric Point (pI)9.84

Net Charge (pH 7.0)9.61

Net Charge (pH 7.4) 9.19

Charge Density (pH 7.0) 0.1012

GRAVY Index-0.24

Hydrophobic Moment 0.63

Boman Index-0.04

Instability Index31.87

Aliphatic Index 71.89

Aromaticity 0.0947

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4369.09

LogP -48.84

H-bond Donors 161.0

H-bond Acceptors 151.0

Rotatable Bonds 348.0

Heavy Atoms 744.0

Ring Count 17.0

Amide Bonds 104.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0224654 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KJ7/entry; https://bblserver.org.in/ampdb/