Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC224H350N64O72S7

DescriptionStandard

        CPGDAHGPDSCNHRGGLCRVGDCVSGEYLAQFCFEPVILCCKNLSLVTTE
    

Molecular Weight5316.02 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-3.12

Net Charge (pH 7.4) -3.54

Charge Density (pH 7.0) -0.0624

GRAVY Index0.08

Hydrophobic Moment 0.49

Boman Index0.10

Instability Index27.00

Aliphatic Index 74.00

Aromaticity 0.0600

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2144.48

LogP -25.30

H-bond Donors 79.0

H-bond Acceptors 78.0

Rotatable Bonds 168.0

Heavy Atoms 367.0

Ring Count 8.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170160 VERIFIED: YES

Provenance & Taxonomy

OrganismSylvia atricapilla [Animal]

FamilyDefensin

Tax ID48155

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

PaperLocus-specific protocol for nine different innate immune genes (antimicrobial peptides: β-defensins) across passerine bird species reveals within-species coding variation and a case of trans-species polymorphisms [PMID:21676198] PMID21676198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21676198/