Peptide Database

Peptide Namebeta-Defensin, DEFB3

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC171H296N58O47S6

DescriptionStandard

        YYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCKKK
    

Molecular Weight4108.93 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)8.70

Net Charge (pH 7.4) 8.39

Charge Density (pH 7.0) 0.2416

GRAVY Index-0.76

Hydrophobic Moment 0.52

Boman Index-0.38

Instability Index43.66

Aliphatic Index 51.39

Aromaticity 0.0556

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1757.49

LogP -20.21

H-bond Donors 71.0

H-bond Acceptors 62.0

Rotatable Bonds 144.0

Heavy Atoms 282.0

Ring Count 3.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0305086 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-32; 10-25; 15-33

Bio-Activity Profile

Function

Antimicrobial