Peptide Database

Peptide NameSLAY-screened peptide P1485

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC25H39N9O14

DescriptionStandard

        DNVDNN
    

Molecular Weight689.63 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.24

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.3730

GRAVY Index-2.22

Hydrophobic Moment 0.44

Boman Index-0.51

Instability Index-16.72

Aliphatic Index 48.33

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 412.69

LogP -6.95

H-bond Donors 12.0

H-bond Acceptors 12.0

Rotatable Bonds 22.0

Heavy Atoms 48.0

Ring Count 0.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118311 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/