Peptide Database

Peptide NameEA1x8

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC92H169N49O32S3

DescriptionStandard

        ACSGSGSGCGSGSGSCGRRRRRRRR
    

Molecular Weight2569.83 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.77

Net Charge (pH 7.4) 7.53

Charge Density (pH 7.0) 0.3106

GRAVY Index-1.37

Hydrophobic Moment 0.39

Boman Index-0.66

Instability Index200.60

Aliphatic Index 4.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1378.30

LogP -27.68

H-bond Donors 59.0

H-bond Acceptors 43.0

Rotatable Bonds 90.0

Heavy Atoms 176.0

Ring Count 0.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066021 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyEA1x8

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0291164 VERIFIED: YES