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MYP_164632
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Basic Information
Cortistatin-29
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitory neuropeptide
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Inhibitory neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Standard
29 amino acids
C149H228N48O42S3
Standard
Sequence
QEGAPPQQSARRDRMPCRNFFWKTFSSCK
Physicochemical Analysis
3459.90 Da
10.09
3.74
3.50
0.1290
-1.28
0.55
-0.38
106.00
6.90
0.1379
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1495.06
-18.09
54.0
49.0
111.0
242.0
8.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007982 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Somatostatin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
17-28
Bio-Activity Profile
Hormone Inhibitory neuropeptide
RECORD: Rec_0013669 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0098802 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Cortistatin
9606
Structure & Mods
linear peptide with reported disulfide constraint [Linear]
canonical L-amino-acid peptide [L]
17-28
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Receptor modulation
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PMID12975309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12975309/
RECORD: Rec_0102204 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 10.3%, E 0.0%, T 41.4%, C 48.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/