Peptide Database

Peptide NameCathelicidin antimicrobial peptide [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC849H1387N243O250S8

DescriptionStandard

        MKTQRDGHSLGWWSLVLLLLGLVMPLAIIAQVLSYKEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARGSFDISCDKDNKRFALLGDFFRKAKEKIGKESKRIVQRIKDFLRNLVPRTES
    

Molecular Weight19255.09 Da

Isoelectric Point (pI)9.36

Net Charge (pH 7.0)6.57

Net Charge (pH 7.4) 6.19

Charge Density (pH 7.0) 0.0386

GRAVY Index-0.43

Hydrophobic Moment 0.97

Boman Index-0.12

Instability Index36.96

Aliphatic Index 87.71

Aromaticity 0.0647

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8022.24

LogP -86.66

H-bond Donors 283.0

H-bond Acceptors 266.0

Rotatable Bonds 655.0

Heavy Atoms 1350.0

Ring Count 23.0

Amide Bonds 181.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0060687 VERIFIED: YES

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyCathelicidin

Tax ID9595

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-MRSA Antibiofilm Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0371075 VERIFIED: YES