Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC751H1170N222O218S5

DescriptionStandard

        MAKVQFTPRKETNAIFVHCAATKPSQDVGVREIRQWHKEKGWLDIGYHFVIRRDGTVEAGREQSAVGSHVANYNHDSVGVCLVGGIDDKGKFAANFTPAQMQSLRSLLVELKVQYPDSALRAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight16957.01 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)3.10

Net Charge (pH 7.4) 2.45

Charge Density (pH 7.0) 0.0205

GRAVY Index-0.50

Hydrophobic Moment 0.75

Boman Index-0.07

Instability Index43.02

Aliphatic Index 74.24

Aromaticity 0.0861

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7097.34

LogP -71.71

H-bond Donors 249.0

H-bond Acceptors 233.0

Rotatable Bonds 561.0

Heavy Atoms 1196.0

Ring Count 30.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0271815 VERIFIED: NO

Provenance & Taxonomy

OrganismYersinia phage vB_YenP_AP10 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic