Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC527H861N153O143S7

DescriptionStandard

        MRLLLIIAILLFQKFTVTEQLKRCWNQYIHGYCRKICRTTEVREVLCENGRYCCINLAELEERKKITKPPRPKLRTLALTFSQDYLIEQNSTHSHRKPT
    

Molecular Weight11852.87 Da

Isoelectric Point (pI)9.57

Net Charge (pH 7.0)8.71

Net Charge (pH 7.4) 8.23

Charge Density (pH 7.0) 0.0880

GRAVY Index-0.43

Hydrophobic Moment 0.73

Boman Index-0.15

Instability Index33.47

Aliphatic Index 94.55

Aromaticity 0.0808

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4856.14

LogP -41.04

H-bond Donors 178.0

H-bond Acceptors 162.0

Rotatable Bonds 402.0

Heavy Atoms 830.0

Ring Count 16.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0324549 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyDefensin

Tax ID9925

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence