MYP_164544
MAC1/20
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antifungal
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
not Standard
13 amino acids
-
contains X representing unresolved or non-standard residue
GFGMALXLLXXVL
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0397548
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 7,10,11
Bio-Activity Profile
Hemolytic
Human umbilical vein endothelial cells HUVEC (IC50 at 33+-3 microM
50 μM
Hemolysis
RECORD: Rec_0403509
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Macropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
O = Ornithine
Bio-Activity Profile
Anticancer
Cytotoxic
HeLa
10±1 μM
IC50
RECORD: Rec_0425619
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 7,10,11
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Escherichia coli B
7.2 μM
MIC
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