Peptide Database

Peptide NameSarafotoxin SRTX-m2

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC123H177N31O42S5

DescriptionStandard

        CSCNDINDKECMYFCHQDIIWDEP
    

Molecular Weight2922.23 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-5.18

Net Charge (pH 7.4) -5.50

Charge Density (pH 7.0) -0.2160

GRAVY Index-0.62

Hydrophobic Moment 0.29

Boman Index-0.05

Instability Index91.02

Aliphatic Index 48.75

Aromaticity 0.1250

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1187.85

LogP -10.69

H-bond Donors 42.0

H-bond Acceptors 43.0

Rotatable Bonds 93.0

Heavy Atoms 201.0

Ring Count 6.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0112287 VERIFIED: NO

Provenance & Taxonomy

OrganismAtractaspis engaddensis [Animal]; Atractaspis microlepidota,microlepidota [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0255027 VERIFIED: YES

Provenance & Taxonomy

OrganismAtractaspis microlepidota microlepidota [Animal]

FamilySarafotoxin-m2

Tax ID172021

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Vasoactive Vasoconstrictor

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour