Peptide Database

Peptide NamePhylloseptin-PV1, PPV1

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC93H160N22O22

DescriptionStandard

        FLSLIPKIAGGIAALVKNL
    

Molecular Weight1938.40 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0925

GRAVY Index1.40

Hydrophobic Moment 0.47

Boman Index0.51

Instability Index4.00

Aliphatic Index 174.74

Aromaticity 0.0526

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 693.69

LogP -2.70

H-bond Donors 23.0

H-bond Acceptors 24.0

Rotatable Bonds 64.0

Heavy Atoms 137.0

Ring Count 2.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0410240 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa vaillantii [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetEnterococcus faecalis NCTC 12697

Activity32 μM

MethodMIC

RECORD: Rec_0427049 VERIFIED: YES