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MYP_164471
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Basic Information
Phylloseptin-PV1, PPV1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C93H160N22O22
Standard
Sequence
FLSLIPKIAGGIAALVKNL
Physicochemical Analysis
1938.40 Da
10.00
1.76
1.55
0.0925
1.40
0.47
0.51
4.00
174.74
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
693.69
-2.70
23.0
24.0
64.0
137.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0179367 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa vaillantii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis NCTC 12697
32 μM
MBC
PMID33193152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33193152/
RECORD: Rec_0196534 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID33193152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33193152/
RECORD: Rec_0214067 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa vaillantii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae ATCC BAA-1705
512 μM
MBC
PMID33193152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33193152/
RECORD: Rec_0218382 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa vaillantii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human squamous lung carcinoma NCI-H157
6.41 μM
IC50
PMID33193152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33193152/
RECORD: Rec_0218836 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa vaillantii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae ATCC 43816
64 μM
MIC
PMID33193152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33193152/
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