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MYP_164471
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Basic Information
Phylloseptin-PV1, PPV1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C93H160N22O22
Standard
Sequence
FLSLIPKIAGGIAALVKNL
Physicochemical Analysis
1938.40 Da
10.00
1.76
1.55
0.0925
1.40
0.47
0.51
4.00
174.74
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
693.69
-2.70
23.0
24.0
64.0
137.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0132965 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID33193152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33193152/
RECORD: Rec_0134466 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa vaillantii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
4 μM
MIC
PMID33193152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33193152/
RECORD: Rec_0145462 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa vaillantii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NCTC 10418
64 μM
MBC
PMID33193152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33193152/
RECORD: Rec_0147477 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa vaillantii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae ATCC BAA-2342
128 μM
MIC
PMID33193152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33193152/
RECORD: Rec_0153403 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa vaillantii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human glioblastoma U251-MG
7.22 μM
IC50
PMID33193152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33193152/
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