Peptide Database

Peptide NameMaximins 3 H14 [Cleaved into: Maximin-3; Maximin-H14]

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antiviral

Antiviral ▸ Anti-HIV

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Reproductive biology ▸ Contraceptive activity ▸ Spermicidal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC709H1167N201O218S3

DescriptionStandard

        MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGKILSGLKTALKGAAKELASTYLHRKRTAEEHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQDEIANLFTKKEKRILGPVLGLVGEPLGGLIKKIG
    

Molecular Weight16091.26 Da

Isoelectric Point (pI)6.76

Net Charge (pH 7.0)-0.29

Net Charge (pH 7.4) -0.66

Charge Density (pH 7.0) -0.0020

GRAVY Index-0.39

Hydrophobic Moment 0.67

Boman Index-0.08

Instability Index42.84

Aliphatic Index 97.57

Aromaticity 0.0556

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6835.74

LogP -65.11

H-bond Donors 239.0

H-bond Acceptors 223.0

Rotatable Bonds 565.0

Heavy Atoms 1131.0

Ring Count 13.0

Amide Bonds 151.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354413 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyBombinin; Maximin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Antiviral Anti-HIV Anti-Candida Cytolytic Cytotoxic Hemolytic Spermicidal

TargetNo Target Organism Found