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MYP_164428
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Basic Information
Magainin-AN2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
23 amino acids
C110H181N29O29S
Standard
Sequence
GVSKILHSAGKFGKAFLGEIMKS
Physicochemical Analysis
2405.86 Da
10.00
2.85
2.59
0.1237
0.24
0.66
0.19
11.96
89.13
0.0870
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
934.27
-7.97
33.0
34.0
85.0
169.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0217808 VERIFIED: NO
Provenance & Taxonomy
Xenopus boumbaensis [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID25849343 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25849343/
RECORD: Rec_0224802 VERIFIED: YES
Provenance & Taxonomy
Xenopus amieti [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
200.0 μM
MIC
PaperJ.M. Conlon et al. / Peptides 31 (2010) 989-994. Orthologs of magainin, PGLa, procaerulein-derived, and proxenopsin-derived peptides from skin secretions of the octoploid frog Xenopus amieti (Pipidae)
RECORD: Rec_0231083 VERIFIED: NO
Provenance & Taxonomy
Xenopus ruwenzoriensis [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID27290612 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27290612/
RECORD: Rec_0286593 VERIFIED: YES
Provenance & Taxonomy
Xenopus andrei [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
100.0 μM
MIC
PaperM. Mechkarska et al. / Comparative Biochemistry and Physiology, Part D 6 (2011) 206-212. Genome duplications within the Xenopodinae do not increase the multiplicity of antimicrobial peptides in Silurana paratropicalis and Xenopus andrei skin secretions
RECORD: Rec_0297153 VERIFIED: NO
Provenance & Taxonomy
Xenopus ruwenzoriensis [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal
Qualitative functional evidence
PMID27290612 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27290612/; https://www.uniprot.org/uniprotkb/C0HKN8/entry; https://bblserver.org.in/ampdb/
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