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MYP_164428
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Basic Information
Magainin-AN2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
23 amino acids
C110H181N29O29S
Standard
Sequence
GVSKILHSAGKFGKAFLGEIMKS
Physicochemical Analysis
2405.86 Da
10.00
2.85
2.59
0.1237
0.24
0.66
0.19
11.96
89.13
0.0870
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
934.27
-7.97
33.0
34.0
85.0
169.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0119767 VERIFIED: NO
Provenance & Taxonomy
Xenopus amieti [Animal] [Animal]; Xenopus fraseri [Animal] [Animal]; Silurana paratropicalis [Animal] [Animal]; Xenopus ruwenzoriensis [Animal] [Animal]; Xenopus boumbaensis [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0138484 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Magainin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial
PMID21498136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21498136/
RECORD: Rec_0148636 VERIFIED: YES
Provenance & Taxonomy
Xenopus andrei [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
100.0 μM
MIC
PaperM. Mechkarska et al. / Comparative Biochemistry and Physiology, Part D 6 (2011) 206-212. Genome duplications within the Xenopodinae do not increase the multiplicity of antimicrobial peptides in Silurana paratropicalis and Xenopus andrei skin secretions
RECORD: Rec_0175136 VERIFIED: YES
Provenance & Taxonomy
Xenopus amieti [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID20226221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20226221/
RECORD: Rec_0199857 VERIFIED: YES
Provenance & Taxonomy
Xenopus andrei [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
100 μM
MIC
PMID21498136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21498136/
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