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MYP_164428
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Basic Information
Magainin-AN2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
23 amino acids
C110H181N29O29S
Standard
Sequence
GVSKILHSAGKFGKAFLGEIMKS
Physicochemical Analysis
2405.86 Da
10.00
2.85
2.59
0.1237
0.24
0.66
0.19
11.96
89.13
0.0870
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
934.27
-7.97
33.0
34.0
85.0
169.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001888 VERIFIED: YES
Provenance & Taxonomy
Xenopus andrei [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
100 μM
MIC
PMID21498136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21498136/
RECORD: Rec_0002823 VERIFIED: YES
Provenance & Taxonomy
Xenopus andrei [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
100 μM
MIC
PMID21498136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21498136/
RECORD: Rec_0063816 VERIFIED: YES
Provenance & Taxonomy
Xenopus amieti [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PMID20226221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20226221/
RECORD: Rec_0089749 VERIFIED: YES
Provenance & Taxonomy
Xenopus amieti [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
50.0 μM
MIC
PaperJ.M. Conlon et al. / Peptides 31 (2010) 989-994. Orthologs of magainin, PGLa, procaerulein-derived, and proxenopsin-derived peptides from skin secretions of the octoploid frog Xenopus amieti (Pipidae)
RECORD: Rec_0117509 VERIFIED: NO
Provenance & Taxonomy
Xenopus boumbaensis [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal
Qualitative functional evidence
PMID25849343 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25849343/; https://www.uniprot.org/uniprotkb/C0HKL6/entry; https://bblserver.org.in/ampdb/
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