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MYP_164416
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Basic Information
28(derived from FIV envelope glycoprotein )
Antimicrobial
Antiviral
Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Standard
20 amino acids
C101H164N34O30S2
Standard
Sequence
RFRIRCRWNVGSDTSLIDTC
Physicochemical Analysis
2398.72 Da
9.02
1.74
1.51
0.0871
-0.40
0.26
-0.26
25.04
73.00
0.1000
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1078.22
-12.51
43.0
34.0
78.0
167.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044540 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-FIV Replication inhibition
Feline immunodeficiency virus (FIV) | fibroblastoid cells
16 μg/mL
% inhibition
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperInhibition of feline immunodeficiency virus infection in vitro by envelope glycoprotein synthetic peptides. | Lombardi S, Massi C, Indino E, La Rosa C, Mazzetti P, Falcone ML, Rovero P, Fissi A, Pieroni O, Bandecchi P, Esposito F, Tozzini F, Bendinelli M, Garzelli C. | Virology. 1996 Jun 15;220(2):274-84. | DOI:10.1006/viro.1996.0315 | PMID:8661378 PMID8661378 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8661378/
RECORD: Rec_0422157 VERIFIED: YES
Provenance & Taxonomy
Feline immunodeficiency virus [Virus]
Virus-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
Feline immunodeficiency virus (Syncytium formation); CrFK
40 %
Syncytia assay
PaperInhibition of feline immunodeficiency virus infection in vitro by envelope glycoprotein synthetic peptides. | Lombardi S, Massi C, Indino E, La Rosa C, Mazzetti P, Falcone ML, Rovero P, Fissi A, Pieroni O, Bandecchi P, Esposito F, Tozzini F, Bendinelli M, Garzelli C. | Virology. 1996 | PMID:8661378 PMID8661378 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8661378/
RECORD: Rec_0423425 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 50.0%, C 50.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/