Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length471 amino acids

Chemical FormulaC2321H3746N602O649S19

DescriptionStandard

        MFLCWCLSLVALIPLTTSTNPGVKVKLTAKGIEYGRQLAVASILQKLKTIKLDDVSGKVRVSIGKVKYSLKNMNMVDVGLPTATLDLVPGTGPKLSIVNANFRLNGNWRVKYRFVKDSGSFKLNGDDISFSTSLSIKTDPTGRPAVSSIDCGANVGKMSVRFRGGASWLYNLFKKSISSAIRKAMQKKICPLVANAVSDLNNNLKTLNVLAKVDKFAEIEYSMVASPAVSKTSIDFGLKGEFYNIGKHQEPPFSPAVFSLPPQINNMLYIGVSSFTIESAAFVYNTAGALSLYITDDMIPKISPIRLNTRTFGVFIPQIAKRFPGLMMKLLVKMAKAPVITFEPNNATVQSFASVTAYAIQPNATLTPLFVLNLVSSVSARVFVSGTRLAGAVTLNKMDLTLGTSYVGDFQVGTLNSIFQTVLNFVVIPRMNAQLAKGYPLPTLGKMKLVNTQLLVLKDHVMIGTDVQFTG
    

Molecular Weight51077.45 Da

Isoelectric Point (pI)9.92

Net Charge (pH 7.0)26.63

Net Charge (pH 7.4) 26.15

Charge Density (pH 7.0) 0.0565

GRAVY Index0.23

Hydrophobic Moment 0.71

Boman Index0.15

Instability Index23.26

Aliphatic Index 102.00

Aromaticity 0.0849

Extinction Coeff. Reduced 34380.00

Extinction Coeff. Oxidized 34630.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0284335 VERIFIED: NO

Provenance & Taxonomy

OrganismGymnodraco acuticeps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria