Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length221 amino acids

Chemical FormulaC1107H1755N283O311S12

DescriptionStandard

        LPMTTQIDAVAGIDYRLVAPPITTAENLDGQLKGEFFSQAHRSPPPFTPPAMAFPEDHDRMVYLGISDYFFNTAGLVYQEAGALKLTLQDHMMPNGSKFLLTTKSLGNVLPQVTKMFPNMKVQLQVSVSTPPQLNTQPTGLTLTPKLEVQAFVVLPNSSLVPLFLLSMDKMVGTRPCQPLPRAEKLKTAFPLPMPARVQLYNLLLQSHQNFLQIGADVNLM
    

Molecular Weight24389.27 Da

Isoelectric Point (pI)8.04

Net Charge (pH 7.0)1.11

Net Charge (pH 7.4) 0.65

Charge Density (pH 7.0) 0.0050

GRAVY Index0.01

Hydrophobic Moment 0.67

Boman Index0.14

Instability Index39.22

Aliphatic Index 93.08

Aromaticity 0.0769

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125828 VERIFIED: NO

Provenance & Taxonomy

OrganismSpermophilus dauricus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence