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MYP_164382
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Basic Information
cBD103
Antimicrobial
Standard
45 amino acids
C216H376N76O61S6
Standard
Sequence
GIINTLQRYYCRIRSGRCALLSCLPKEEQIGRCSSTGRKCCRRKK
Physicochemical Analysis
5206.16 Da
10.10
9.70
9.40
0.2156
-0.66
0.75
-0.36
66.53
71.56
0.0444
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2299.92
-27.89
92.0
77.0
182.0
359.0
3.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0062919 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa ATCC 27853; Proteus hauseri ATCC 13315; Enterococcus faecalis clinical isolate
>64 μM
MIC
PaperExploring Pleiotropic Functions of Canine beta-Defensin 103: Nasal Cavity Expression, Antimicrobial Activity, and Melanocortin Receptor Activity. PMID31714028
RECORD: Rec_0163810 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. pseudintermedius clinical strain, methicillin resistant MRSA
8 μM
MIC
PaperExploring Pleiotropic Functions of Canine beta-Defensin 103: Nasal Cavity Expression, Antimicrobial Activity, and Melanocortin Receptor Activity. PMID31714028
RECORD: Rec_0181506 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. pseudintermedius clinical strain, no resistance
16 μM
MIC
PaperExploring Pleiotropic Functions of Canine beta-Defensin 103: Nasal Cavity Expression, Antimicrobial Activity, and Melanocortin Receptor Activity. PMID31714028
RECORD: Rec_0189266 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923; methicillin-resistant Staphylococcus aureus (MRSA)
>64 μM
MIC
PaperExploring Pleiotropic Functions of Canine beta-Defensin 103: Nasal Cavity Expression, Antimicrobial Activity, and Melanocortin Receptor Activity. PMID31714028
RECORD: Rec_0340237 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922; resistant Escherichia coli clinical strains
>64 μM
MIC
PaperExploring Pleiotropic Functions of Canine beta-Defensin 103: Nasal Cavity Expression, Antimicrobial Activity, and Melanocortin Receptor Activity. PMID31714028
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