Peptide Database

Peptide NameCycloviolacin VY1

Function Ontology

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Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC122H198N34O37S6

DescriptionStandard

        CGESCVWIPCLTATIGCSCKSKVCYRN
    

Molecular Weight2925.47 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0630

GRAVY Index0.38

Hydrophobic Moment 0.26

Boman Index0.10

Instability Index33.76

Aliphatic Index 68.52

Aromaticity 0.0741

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1142.63

LogP -13.51

H-bond Donors 47.0

H-bond Acceptors 45.0

Rotatable Bonds 92.0

Heavy Atoms 199.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0051509 VERIFIED: YES

Provenance & Taxonomy

OrganismViola baoshanensis [Plant]

FamilyCyclotide

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)