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MYP_164343
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Basic Information
Mastoparan-VT2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C64H119N17O15
Standard
Sequence
NLKAIAALAKKLL
Physicochemical Analysis
1366.73 Da
10.30
2.76
2.55
0.2121
0.90
0.58
0.22
-3.83
180.77
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
533.67
-2.21
18.0
18.0
49.0
96.0
0.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0307801 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Klebsiella pneumoniae ATCC 700603
20 μM
MIC
PaperAntimicrobial peptides from the venom gland of the social wasp Vespa tropica.
RECORD: Rec_0310280 VERIFIED: YES
Provenance & Taxonomy
Vespa mandarinia [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
40 μg/mL
MIC
PMID24012601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24012601/
RECORD: Rec_0314927 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Enterococcus faecalis ATCC 29212
5 μM
MIC
PaperAntimicrobial peptides from the venom gland of the social wasp Vespa tropica.
RECORD: Rec_0315848 VERIFIED: YES
Provenance & Taxonomy
Vespa mandarinia [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae
10 μg/mL
MIC
PMID24012601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24012601/
RECORD: Rec_0321670 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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