Peptide Database

Peptide NameHepcidin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC432H681N123O125S14

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPFAGVQELEEAGSNDTPVAAHQEMSMESWMMPNHISRQKRQSHLSLCRWCCNCCRGNKGCGFCCKF
    

Molecular Weight10046.69 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0075

GRAVY Index0.17

Hydrophobic Moment 0.66

Boman Index0.10

Instability Index66.32

Aliphatic Index 71.87

Aromaticity 0.0769

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3953.60

LogP -41.54

H-bond Donors 145.0

H-bond Acceptors 143.0

Rotatable Bonds 331.0

Heavy Atoms 694.0

Ring Count 15.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354366 VERIFIED: NO

Provenance & Taxonomy

OrganismDicentrarchus labrax [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence