Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC57H87N21O11

DescriptionStandard

        WWVAARAARR
    

Molecular Weight1242.43 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.56

Charge Density (pH 7.0) 0.2760

GRAVY Index-0.39

Hydrophobic Moment 0.66

Boman Index-0.24

Instability Index57.79

Aliphatic Index 69.00

Aromaticity 0.2000

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 542.50

LogP -3.27

H-bond Donors 22.0

H-bond Acceptors 14.0

Rotatable Bonds 36.0

Heavy Atoms 89.0

Ring Count 4.0

Amide Bonds 9.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0407273 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Confighydrocarbon-stapled side-chain cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermValerylamide

C-TermAmidation

Other ModsThe Ⓧ (position: 4 and 8) in sequence indicates (S)-2-(4'-pentenyl)-alanine. Ⓧ (4) and Ⓧ (8) are cross-linked by hydrocarbon stapling through an oct-4-enyl hydrocarbon staple

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 700926

Activity14.8 μM

MethodIC50

RECORD: Rec_0420621 VERIFIED: YES