Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC225H360N56O71S4

DescriptionStandard

        MKGVKEKKELFDLDVKVNAKEIDDSESGPPPNTSLIWCTPGCAKYM
    

Molecular Weight5113.86 Da

Isoelectric Point (pI)5.14

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.78

Charge Density (pH 7.0) -0.0329

GRAVY Index-0.60

Hydrophobic Moment 0.47

Boman Index-0.06

Instability Index47.44

Aliphatic Index 65.65

Aromaticity 0.0652

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2041.55

LogP -18.60

H-bond Donors 69.0

H-bond Acceptors 74.0

Rotatable Bonds 171.0

Heavy Atoms 356.0

Ring Count 8.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0342661 VERIFIED: NO

Provenance & Taxonomy

OrganismStaphylococcus sp. HMSC036D05 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria