Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length201 amino acids

Chemical FormulaC1011H1527N227O312S8

DescriptionStandard

        PIPIDDLAEIDYSLNSLPAVSQPYIDLDLKGIVYPGGNYSAPSFEAAPFTVPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVGQYSVTPYPVMLKLMATETPIISLQQDSFTLEILGSMEVFAVLPDSSTQSLFTMSIAANTSIAVNIFDQKLMGSLCLNRLQYSLTRSNVGFFEV
    

Molecular Weight22109.79 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-16.03

Net Charge (pH 7.4) -16.17

Charge Density (pH 7.0) -0.0798

GRAVY Index0.28

Hydrophobic Moment 0.64

Boman Index0.25

Instability Index51.13

Aliphatic Index 93.18

Aromaticity 0.1343

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008632 VERIFIED: NO

Provenance & Taxonomy

OrganismTinamus guttatus [Animal]

FamilyBPI/LBP

Tax ID94827

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria