Peptide Database

Peptide NameDQ2-y -II y-Glia (p222p236; E229)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC72H122N22O22

DescriptionStandard

        GQGIIQPEQPAQLIR
    

Molecular Weight1647.87 Da

Isoelectric Point (pI)6.00

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0158

GRAVY Index-0.46

Hydrophobic Moment 0.32

Boman Index0.02

Instability Index66.62

Aliphatic Index 110.67

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 724.70

LogP -7.14

H-bond Donors 22.0

H-bond Acceptors 22.0

Rotatable Bonds 54.0

Heavy Atoms 116.0

Ring Count 2.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0305409 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E229

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay