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MYP_164173
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Basic Information
DRP-PBN2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C108H185N29O33
Standard
Sequence
GLVTSLIKGAGKLLGGLFGSVTGGQS
Physicochemical Analysis
2417.80 Da
10.00
1.76
1.55
0.0676
0.70
0.59
0.38
9.88
116.15
0.0385
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
987.10
-12.32
35.0
35.0
83.0
170.0
1.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0156212 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
6.25 μM
MIC
PaperP. Nicolas and C. El Amri / Biochimica et Biophysica Acta 1788 (2009) 1537-1550. The dermaseptin superfamily: a gene-based combinatorial library of antimicrobial peptides Evidence URLhttps://www.uniprot.org/uniprotkb/Q800R4/entry
RECORD: Rec_0158295 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Klebsiella pneumoniae
0.8 μM
MIC
PMID12709067;15222751 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12709067/
RECORD: Rec_0163286 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Aerococcus viridans
3.1 μM
MIC
PMID12709067;15222751 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12709067/
RECORD: Rec_0163982 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterobacter cloacae
12.5 μM
MIC
PMID12709067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12709067/
RECORD: Rec_0197856 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Salmonella typhimurium
3.1 μM
MIC
PMID12709067;15222751 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12709067/
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