Peptide Database

Peptide NameSLAY-screened peptide P567

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC101H156N26O30S

DescriptionStandard

        PCTRSTLSPPNFVVELVSNW
    

Molecular Weight2246.54 Da

Isoelectric Point (pI)6.39

Net Charge (pH 7.0)-0.05

Net Charge (pH 7.4) -0.12

Charge Density (pH 7.0) -0.0024

GRAVY Index0.05

Hydrophobic Moment 0.44

Boman Index0.13

Instability Index62.90

Aliphatic Index 82.50

Aromaticity 0.1000

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 886.97

LogP -9.38

H-bond Donors 32.0

H-bond Acceptors 31.0

Rotatable Bonds 65.0

Heavy Atoms 158.0

Ring Count 6.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294594 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/